However, historically, HCWs are reluctant to get vaccinated, when considering the seasonal influenza vaccination campaigns: from 2015 to 2018 the European uptake was below 40%. Previous research demonstrated higher mortality rates in clinical settings where employees’ vaccine uptake was lower. Vaccination among HCWs and healthcare students with access to clinical settings is pivotal to both providing HCWs and students’ safety and patient safety. The pandemic also affected healthcare workers (HCWs) worldwide impacting on healthcare provision through staff absence and illness. In this rapidly evolving scenario, an in-depth understanding of vaccine hesitancy with a focus on the development of future, more effective strategies to promote adherence to vaccination remains a priority. Nevertheless, updated vaccines could reverse this trend. It is important to note that, nowadays, vaccine uptake tends to decrease globally with each additional recommended dose. However, different variant-updated vaccines are under clinical development to enhance the magnitude, duration, and breadth of immunity afforded by COVID-19 vaccines to achieve public health impact now and in the future. To date, current vaccines continue to prevent severe disease and death despite several variants of concern (VOC) that appear to spread faster than the initial SARS-CoV-2 strain. Public interest in vaccines has increased dramatically and at an unprecedented level following the COVID-19 pandemic. Globally, as of 17 June 2022, there have been over 535 million confirmed cases of COVID-19 and 6,314,972 deaths. The coronavirus disease 2019 (COVID-19) pandemic has been considered the most pressing global issue impacting every aspect of people’s lives. The funder had and will not have a role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist. There was no additional external funding received for this study. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data from this study will be made available upon study completion.įunding: This study has been supported by an internal funding provided by Northumbria University at Newcastle (UK) ( ). Received: JAccepted: MaPublished: March 31, 2023Ĭopyright: © 2023 McCready et al. PLoS ONE 18(3):Įditor: Muhammad Shahzad Aslam, Xiamen University - Malaysia Campus: Xiamen University - Malaysia, MALAYSIA The outcomes of this review will have wide-reaching implications for the research area, healthcare systems and institutions, and governments worldwide.Ĭitation: McCready J, Comparcini D, Nichol B, Steen M, Unsworth J, Tomietto M (2023) Understanding the barriers and facilitators of COVID-19 vaccine hesitancy amongst healthcare workers and healthcare students worldwide: An umbrella review protocol. The degree to which the included reviews contain the same primary studies will also be assessed and reported. The Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Systematic Reviews and Research Syntheses will be used to assess the methodological quality of the included reviews. The screening processes and data extraction will be conducted independently by two reviewers. Studies will be eligible for inclusion if they: (i) conducted a systematic review (with or without meta-analysis) (ii) included primary sources utilizing a quantitative methodology (iii) investigated factors related to COVID-19 vaccine hesitancy (iv) and included a sub/population of HCWs or healthcare students aged 18–65. The databases that will be searched are CINAHL, MedLine, Cochrane Library, PubMed, ProQuest, Web of Science, Science Direct, IBSS, Google Scholar, and Epistemonikos. The current protocol describes the methodology for an Umbrella Review that explores the barriers and facilitators of COVID-19 vaccine hesitancy for HCWs and healthcare students. Understanding and designing effective strategies to promote vaccination among HCWs is pivotal to secure an appropriate and safe healthcare provision. However, a comprehensive overview of barriers and facilitators of COVID-19 vaccine hesitancy is greatly needed to address effective interventions in this population. The factors related to vaccine hesitancy have been reported in several systematic reviews. Vaccination efforts amongst this group of persons have been hampered in some countries by hesitancy to uptake the COVID-19 vaccine. Healthcare workers (HCWs) and healthcare students are at increased risk of becoming infected with and being a vector of transmission of COVID-19.
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